Research Services

We provide our customers excellent research services and access to important and latest molecular tools for their business. Our fully automated instrumentation offers rapid turnaround time and accurate results. Our experienced staff includes highly skilled molecular biologists, geneticists, biochemists, and statisticians. We take up projects from simple testing and delivering results to offering turn key solutions to your research projects.

Medical and Drug Research

Gene Expression studies using Real time quantitative PCR technology: Gene expression is studies using syber green, Taqman or MolecularBeacon probes in understanding specific gene expression with disease progression, cancer minimal residual disease, drug response, invivo carcinogen treated gene studies in mice and lab animals, in vitro pre-clinical trials etc.

Genetic toxicology in response to drug/ chemical / radiation:  Genetic toxicology studies to study the effect of DNA damage and repair capabilities by using Ames, Sister chromatid exchanges, DNA/chromosome breakage studies, Single cell gel electrophoresis etc.

Genetics of polygenic and multifactorial diseases:  Population specific genetic research is important to detect genetic variation and polymorphism for common health conditions like cardiovascular diseases, Diabetes, Asthama and physiatric disorders. Various PCR based technologies (ARMS, nested PCR, long PCR), mutation detection methods (mini sequencing method, DGGE, TGGE) are used for such research.

Protein expression studies: Qualitative and quantitative measurement of proteins in different tissues is studied by using biochemical technologies like ELISA, Chemiluminescence and Time resolved Flourimetry.

Basic research, epidemiological and community studies on genetic disorders: In collaboration with hospitals, government and voluntary bodies GeneTech conducts basic research and population surveys for various common and unique genetic disorders in Indian population.

Plant and Veterinary Research

DNA fingerprinting: Genetic profiles are developed for plant hybrids and animal species by the application of different molecular fingerprinting tools like STR (Single tandem repeats or Microsatellites and RAPD (Randomly amplified polymorphic DNA). DNA fingerprinting is a very useful tool for implementing intellectual property rights, testing for specific genes, hybrid verification, and for getting approval for varieties from government bodies. We presently work with cotton, sunflower, and safflower hybrids in our laboratory.

Genetic up gradation of crops through biotechnology and genetic engineering tools: Integration of biotechnology marker selection techniques with conventional and traditional breeding approaches offers great promise for plant breeding. Marker assisted plant breeding management is done to identify and develop markers for traits of economic values such as resistance to pathogens, insects and nematodes, tolerance to antibiotic stress etc; to improve quality and productivity; to provide patent protection of the technology developed and to screen for susceptibility/resistance to various agricultural pathogens. Different molecular markers like RAPD, DAF, SSR, AFLP, AP-PCR, Microsatellites are used.

Molecular detection of Plant and Animal viruses: Plant, Fish and other animal pathogen/viral gene expression is studied in response to treatment, environment and genetic factors. Gene expression studies are undertaken to understand which genes are active in particular tissues at particular times and access the relative degrees of activity of the genes. We use relatively new and highly sensitive Real time Quantitative PCR is for Gene expression studies.

Protein expression studies:  Protein expression of genetically modified crops, food is studied and protocols are develop for detection and quantification of the pure or unidentified protein form in plants and animals. Biochemical technologies like ELISA (Enzyme Linked Immuno Sorbant Assay) and Time Resolved Flourimetry and Iso-Electric focusing are used in the research studies.

Development of molecular testing alternatives for GOT (grow out test):  Molecular marker based testing/fingerprinting will provide a quicker and sensitive alternative to much expensive and time consuming grow out test. Our lab is engaged in identifying the tools for the application in collaboration with international laboratories.

Please write to research@genetech.co.in for your research requirements.